Synthetic Graft Particulate

Hydroxyapatite, Ca10(PO4)6(OH)2 is a hydrated calcium phosphate, major component (about 95%) of the mineral phase of human bones and teeth. Used by the body to make up the skeleton due to its capacity to act as a calcium and phosphorus reserve. Due to its chemical similarity with the chemical phase of bone tissues, it is one of the most biocompatible materials known, promoting bone growth in regions where it is found (osteoconductive), establishing chemical bonds between it and the bone tissue (bioactive), allowing the proliferation of fibroblasts, osteoblasts and other bone cells, which are not different from the bone surface indicating a high surface chemical similarity.

The surface of the hydroxyapatite allows the integration of bipolar alloys, causing water molecules, proteins and collagen to be absorbed on the surface, thereby inducing tissue regeneration. The application of Hydroxyapatite enables the restoration of bone tissue through the osteoconduction process.

Hydroxyapatite is a synthetic material composed of macro and nano pores with low substitution rate. It is used for bone tissue regeneration and can be used in combination with autogenous bone, PRP and PRF.

The Bionnovation Hydroxyapatite has up to 80% of interconnected porosity to support the formation of vascularized bone. Its low substitution rate helps provide the long- term stability of the graft and maintain volume when necessary for a longer period of time. The Bionnovation Hydroxyapatite is a synthetic alternative but with chemical and structural features similar to the Xenogenous bone substitutes.

The hydroxyapatite-based biomaterials have been widely used in bone replacement. Hydroxyapatite is a bone graft material indicated with success in orthopedic, cranio- maxillofacial and dental surgeries. It is recommended for the repair of cranial base defects, spinal fusion and orthopedic applications, besides bone graft around dental implants and metal hip prostheses.



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